Revisions marked with
This course consists of a study of DNA, genes, inheritance, genetic variation, genetic architecture, and change within and among populations. Population based topics will include genetic variation, its importance, how it originates and is maintained as well as inbreeding, random mating, mutation, migration, selection, genetic drift, the effects of small population size, fitness, population subdivision, kin selection, neutral theory, and molecular evolution.
| Meeting Location: | |
| Meeting Time: | Tues/Thurs 12:30-1:45pm |
| Credits | 3 |
| Required texts | Principles of Population Genetics by Hartl and Clark, ISBN 978-0-87893-308-2 |
| Essentials of Genetics by Klug et al., ISBN 978-0-13-489841-4 | |
| Instructor: | Michael Osier |
| Office: | GOS 1338 |
|
| |
| Contact: | COS Directory |
Under certain circumstances, the instructor may have to alter course requirements, assignment deadlines, and grading procedures; and the university may have to alter the term calendar.
| Note that topics in weeks 10 and later would shifted down one week. The board game and open discussion were removed to make room. |
Assigned readings are due before class. There are additional required readings in myCourses under Content which are post-lecture readings.
Tuesday |
Thursday |
|||||
| Week 1 Jan 14 |
Introduction; Nature of Phenotypic Variation (Hartl: Chapter 1.1-1.3) | Genome structure and replication, karyotypes, typical gene structure (Klug: Chapters 2.1-2.6, 6) | Introduction to Spreadsheets | |||
| Week 2 Jan 21 |
Genetic variation (Klug: 6, 14.1-14.4, 13.8) | Quiz 1 | Genetic variation (Klug: 6, 14.1-14.3, 13.8) | |||
| Week 3 Jan 28 |
Homework 1 | Transcription and Translation (Klug: Chapters 12.1-12.4, 12.6-12.12, 13.1-13.2, 13.4) | ||||
| Week 4 Feb 4 |
Quiz 2 | Common statistics (ChiSq Worksheet) | Mendelian transmission | Quiz 3 | Independent Assortment (Klug: 3.1-3.4, 3.6-3.8) | |
| Week 5 Feb 11 |
Homework 2 | Genotyping (Hartl: pp. 18-20 [Allele Freq and Geno Freq, Polymorph and Heterozyg) | Random mating and HWE (Hartl: Chapter 2.1-2.4) | Quiz 4 | Epistasis and Penetrance | Exam review |
| Week 6 Feb 18 |
Exam 1 | Recombination and Independent Assortment | Linkage and linkage disequilibrium (Hartl: Chapters 2.5-2.6, 10.1, 10.3) | |||
| Week 7 Feb 25 |
Linkage and linkage disequilibrium (Hartl: Chapters 2.5-2.6, 10.1, 10.3) | Mapping by recombination (Klug: 7.1-7.4) | Quiz 5 | Mapping by recombination (Klug: 7.1-7.4) | Random genetic drift (Hartl: pp. 95-111) | |
| Week 8 Mar 3 |
Homework 3 | Inbreeding (Hartl: Chapter 6.1) | Quiz 6 | Inbreeding, Population substructure, assortative mating (Hartl: Chapters 6.1-6.4, 10.4) | ||
| Week 9 Mar 10 |
Spring Break | |||||
| Week 10 Mar 17 |
||||||
| Week 11 Mar 24 |
Homework 4 | Effects of new mutation (Hartl: Chapter 4.1) | Migration (Hartl: Chapter 6.5) | Quiz 7 | Migration (Hartl: Chapter 6.5) | Selection and HWE (Hartl: pp. 200-223) |
| Week 12 Mar 31 |
Selection and HWE (Hartl: pp. 200-223) | Mutation/Selection balance (Hartl: Chapters 5.4, 10.5), | Quiz 8 | Homework 5 | Mutation/Selection balance (Hartl: Chapters 5.4, 10.5), Exam review | |
| Week 13 Apr 7 |
Exam 2 | Kin selection (Hartl: pp. 243-5) | Drift and molecular evolution (Hartl: pp. 158-178, 7.1) | |||
| Week 14 Apr 14 |
Homework 6 | Modes and patterns of selection | Measuring differences in survival and reproductive success | Quiz 9 | Measuring differences in survival and reproductive success | Predicting evolutionary response to forces |
| Week 15 Apr 21 |
Quiz 10 | Predicting evolutionary response to forces | Adaptive significance of sex | Quiz 11 | Adaptive significance of sex | Conservation genetics (Philippine reef fish,Fish DNA barcoding in Taiwan, Fish DNA barcoding in South Africa) |
| Week 16 Apr 28 |
Reading day | Homework 7 due, Final exam 1:30-4pm | ||||
| Homework (6 points each x 7) | 42% |
| Weekly quizzes (1 point each x 11) | 11% |
| Exam 1 | 15% |
| Exam 2 | 15% |
| Final Exam | 17% |
| Total | 100% |
|---|
|
No electronics except for a calculator. The calculator must not be a graphing or programmable calculator. No caps or hats. You will have the full period to finish the exam, and there will be no lecture on exam days. All quizzes will be give in myCourses under the Quiz section. The quiz can be started between 8am and 12pm on the given date, and you will have 30 minutes to complete it. For Exam 2, the short answer sections will be given in the myCourses Quiz section at 8am to 1pm on the given date, and you will have 30 minutes to complete it. The long answer questions will be in the myCourses Content, and will open up at 12:30pm on the given date. Long answer questions must be filled out on paper. You may take pictures of your answers with a smart phone or similar device, or you may scan them in. Long answers must be submitted to the appropriate Assignment box in myCourses by 2pm on the given date. This gives you 1.5 hours to finish these longer problems. The Final Exam will be given in the same manner as Exam 2 on Thursday, April 30th, as previously scheduled. However, the short answer will be open for the full exam period (1:30-4pm), and the long answer will be given two hours (2-4pm) for completion. The final exam day and/or time may need to change if the Institute dictates.
Starting on the morning of Monday, March 23rd through 11pm on Wednesday, March 25th, there will be an Assignment box on myCourses open for you to test submitting long answer problems. Please try drawing something, scanning or taking a picture of it, and submitting it to the Assignment box. :) |
If needed, only one quiz/exam makeup will be given per assessment, at a day and time to be determined by the instructor. So all students needing a makeup will take the makeup on the same date, time, and location. Let the instructor know as far in advance as possible if you need to take a makeup.
Students are expected to attend all classes. If a class is missed, students are expected to contact the instructor with specific questions about what was missed based upon the slides and assigned readings.
Students are expected to participate in all discussions. This is a valuable opportunity to ensure that you understand the course material..
For the first offense, anyone caught plagiarizing or otherwise cheating will receive a 0 (zero) on the assignment/quiz/exam, and be referred to the Head of the School of Life Sciences. In the event of a second offense, the student will receive an "F" for the course. If you have any questions about whether or not something constitutes plagiarism and/or cheating, please ask the instructor in advance. Duplicate submissions will also receive a grade of 0 (zero) for the first incident. In the case of especially egregious offenses, the instructor reserves the right to assign a grade of "F" for the course, as per RIT policy.
Contents last updated 3/26/20