Genetics - Summer 2024

Evolving Syllabus

Subject to some change during the course of the semester. Under certain circumstances, the instructor may have to alter course requirements, assignment deadlines, and grading procedures; and the university may have to alter the semester calendar.


Prerequisites


Administrative details

Meetings:MWF 10:30am-12:40pm, Online Zoom
RecitationsMWF 9-9:50am, Online Zoom
Credits3
Required text Essential Genetics, 7th ed, by Hartl and Jones
Instructor:Michael Osier
Office:Online
Schedule
Contact:mvoscl@rit.edu

Online course expectations

Students are expected to read this entire syllabus and understand it before the first day of class. If you have any questions about the expectations, please email them to the instructor before the first class session. You can find the instructor's email address in our myCourses shell under Classlist.

For this course, you will see that some sessions, or portions of sessions, will require attendance on Zoom at a scheduled time. These sessions in the table below will be colored green or grey.

Other sessions, in blue, red, or yellow, will require outside activity to be done on your own, sometimes at the scheduled time. Instructions for these sessions will be posted and/or emailed in advance.

For red exam times, a Zoom session will be available to ask questions. I recommend joining that Zoom at the start of the exam time in case there are any announcements, such as clarifications.

In this course, I will be your guide. What you learn from this course depends on the effort that you put in. In addition to our in person sessions, there will be many opportunities to ask questions such as email, office hours, class time, and online discussions. Please take advantage of those opportunities.


Topics

GreenZoom lecture - attendance required
YellowOnline self-directed activity
GrayZoom recitation - attendance required
BlueOnline quiz at scheduled time - 10 minutes
RedOnline exam at scheduled time
BlackNo class

Monday morning

Monday

Wednesday morning

Wednesday

Friday morning

Friday

9-9:50am 10:30am-10:40am 10:40am-12:40pm 9-9:50am 10:30am-10:40am 10:40am-12:40pm 9-9:50am 10:30am-10:40am 10:40am-12:40pm
Week 1 - May 13th No class Welcome and open questions Introduction; Why study genetics?; Phenotypic Variation; Mendel and Darwin (Chapter 2.1-2.6; Chapter 15.1-15.2) Activity: NIH Genetic Testing Registry Quiz 1 Genome structures; Organization of the Chromosome; Mitosis and Meiosis; Mutation and Repair; Eukaryotic gene structure; Polymorphism (Chapters 3.1-3.5, 5.3, 6.1-6.5, 12.1-12.6) CoT in the Act by Dr. Rothman
Week 2 - May 20th Quiz 2 Model organisms; Sex-linked inheritance; Sex determination and the Lyons hypothesis; (Chapters 3.6, 5.1-5.2) Activity: sex-linked Drosophila phenotypes Quiz 3 Trancription, splicing, and translation (Chapter 8) Exam review packet Exam review session Exam 1
Week 3 - May 27th No class - Holiday Exam 1 debriefing Prokaryotic gene expression (Chapter 9.1-9.3) Homework review session Quiz 4 Mapping prokaryotic genes (Chapter 7.1-7.5)
Week 4 - June 3rd Prokaryotic mapping problems Quiz 5 Eukaryotic gene expression (Chapter 9.4-9.7) Independent assortment (Chapter 2.3-2.4, 3.7) Quiz 6 Independent assortment (Chapter 2.3-2.4, 3.7) Recombination; tetrad analysis Independent assortment practice Quiz 7 Linkage (Chapter 4.1-4.2, 4.4-4.5)
Week 5 - June 10th Exam review session Exam 2 Activity: finding double-recombinants Segregration analysis; Eukaryotic gene mapping; Karyotype analysis; Quantitative genetics (Chapters 2.5, 4.1-4.3, 15.1-15.2, 15.5) Mapping problem packet Quiz 8 Introduction to Population Genetics: Random mating, non-random mating, and HWE; (Chapters 14.2-14.3, 14.9) Activity: Forensics and HWE
Week 6 - June 17th Quiz 9 Random Genetic Drift; HWE and Selection (Chapters 14.2-14.3, 14.9) No class - Holiday Exam review session Exam 3
Week 7 - June 24th Population genetics practice problem Complementation (pp 16-19); Pleiotropy and Penetrance and Phenocopies, oh my! (Chapter 2.7) Exam review packet Quiz 10 Review session Final Exam


Grading

Bonus points are available for homework assignments.

Quizzes (2 points each x 10)20 pts
Lecture questions and attendance12
Exam 114
Exam 218
Exam 318
Final Exam18
Total100 pts

If your final exam grade is higher than your average for the first two exams, your final exam grade will replace your lowest grade in Exams 1 and 2. So if you earn 90% on your final, and your average was 83%, and your lowest grade was a 70%, the 90% will replace the 70%, plus you get a 90% on the final.
There will be no other makeup assignments without extreme circumstances. See Quiz and Exam policy below for other ways quizzes and exams may be made up.


Lecture questions

Each day of lecture (green above) will include a Q&A session. As part of your participation points, you must submit at least three questions about the readings and/or slides from the previous lecture section to the appropriate Assignment box before midnight the night before that session. So the first questions are due on Friday of Week 1 and would be regarding the lecture Week 1 on Wednesday. You must also attend all noted sessions (green and grey) via Zoom, stay for the period, and answer all Zoom polls.

You must post the Q&A questions for at least eight class sessions in green. There are plenty of opportunities to earn this credit, but also some breaks in the schedule to allow you flexibility. I strongly suggest earning the credit as quickly as possible, in case an emergency comes up later in the course. The questions will not be accepted late, as there are many opportunities to get them in.


Homework assignments

The below homework questions may be reflective of some questions on quizzes and exams.

All numbers below are Concepts in Action problems from the end of the corresponding chapter. "2.1" corresponds to Chapter 2, first Concept in Action problem. All even numbered problems have answers in the back of the text. Problems from outside the textbook may also be indicated.

All HW assignments are due by 9am on the next class date. Every completed HW assignment is worth 0.5 bonus pts on your final grade. HW must be submitted to the appropriate Assignment box on myCourses. MS Word/MS Excel/OpenOffice/LibreOffice formats are preferred. However, you may submit as a common image format (PNG/JPEG/GIF/TIFF/BMP) or PDF also. You do not need to restate the question. Just be sure it is obvious which answer is for which assigned problem.

WeekDay AssignedDay DueAssignment
1 Wednesday Week 1 Friday 2.1, 2.2, 2.5, 2.16, 2.20; Search OMIM for a disease of interest to you...in no more than one-half page, single-spaced, describe what is known about the genetics of this human trait.
Friday Week 2 Monday 3.2, 3.8, 6.4, 6.6, 6.8, 6.10
2 Monday Week 2 Wednesday None
Wednesday Week 2 Friday 2.18, 3.10, 3.12, 5.4, 5.6, 5.8, 8.2, 8.6, 8.8, 8.14, 8.20, 12.2, 12.6, 12.8, 12.12, 12.16
3 Wednesday Week 3 Friday 9.2, 9.16, 9.18
Friday Week 4 Monday 9.6, 7.10, 7.14, 7.18, 7.20
4 Wednesday Week 4 Friday 3.16, 3.18
Friday Week 5 Monday 4.2, 4.6, 4.8, 4.10
5 Wednesday Week 5 Friday 2.8, 2.9, 2.10, 2.21, 4.20 a & b, 5.12
Friday Week 5 Monday 14.2, 14.4, 14.6, 14.8, 14.10, 14.12
6 Monday Week 6 Friday Worksheet in myCourses
7
Wednesday Start of final exam Due before the final: 2.3, 2.11, 2.15, 4.17, 9.13, 9.20, 12.9, 12.11, 14.9, 14.17, 2.13, 4.11, 4.14, 4.19, 9.15, 12.17, 14.11, 14.13, 14.15, 15.5

Quiz and Exam policy

Quizzes must be completed within the allotted time.

If more than one person needs a makeup for a specific quiz/exam, everyone will take the makeup on a single day/time. If possible, please email the instructor as soon as possible before the quiz/exam, or as soon as possible after.


Links

Spreadsheets to practice with

Supporting information


Contents last updated 6/23/24