Genetics - Spring 2026


Evolving Syllabus

Subject to some change during the course of the semester. Under certain circumstances, the instructor may have to alter course requirements, assignment deadlines, and grading procedures; and the university may have to alter the semester calendar.


Tentative Syllabus!

Subject to change before start of Spring semester


Prerequisites


Administrative details

Meetings:MWF 9-9:50am, location TBD (**)
Recitation (also required attendance)Wednesday 8-8:50am, location TBD (**)
Credits3
Required text iClicker will be required.
Optional text Genetics: From Genes to Genomes, 8th Edition, ISBN 978-1-266-11559-2
Instructor:Michael Osier
Office:08-1338
Schedule
Contact:mvoscl@rit.edu

Topics

Mon lecture

Wed recitation

Wed lecture

Fri lecture

Week 1 - Jan 12 Introduction; Why study genetics?, Phenotypic Variation Mendel and Darwin (Chapters 1-2; look over OMIM) Quiz 1 Genome structures; Organization of the Chromosome; Mitosis and Meiosis (Chapters 3, 6.3-4, 13)
Week 2 - Jan 19 No class CoT in the Act by Dr. Rothman Mutation and Repair; Eukaryotic gene structure (Chapter 7) Polymorphism (Chapter 12.1); Model organisms
Week 3 - Jan 26 Quiz 2 Sex-linked inheritance; Sex determination and the Lyons hypothesis (Chapter 4) Activity: sex-linked Drosophila phenotypes, Exam review Trancription, splicing, and translation (Chapter 9.1)
Week 4 - Feb 2 Exam 1: short answer Online activity this week - NIH Genetic Testing Registry Exam 1: problem solving Exam 1 followup
Week 5 - Feb 9 Prokaryotic gene expression (Chapter 18) Mapping prokaryotic genes (Chapter 16.2-16.4) Quiz 3 Mapping prokaryotic genes Mapping prokaryotic genes; Eukaryotic gene expression (Chapter 19)
Week 6 - Feb 16 Quiz 4 Independent assortment (Chapter 1, p. 141 Tools of Genetics) Parada et al., 2002 Independent assortment)
Week 7 - Feb 23 Quiz 5 Tetrad analysis (Chapter 5.1, 5.2, 5.5) Exam review Linkage (Chapter 5.3)
Week 8 - Mar 2 Exam 2: short answer Online activity this week - Prokaryotic mapping practice worksheet Exam 2: problem solving Exam 2 followup
Week 9 - Mar 9 Spring Break
Week 10 - Mar 17 Segregration analysis (Chapter 1.3, pp. 380-381 Tools of Genetics) Mid-semester review Eukaryotic gene mapping; Karyotype analysis (Chapter 5.3) Quantitative genetics (Chapter 25.1)
Week 11 - Mar 23 Quiz 6 Introduction to Population Genetics: Random mating, non-random mating, and HWE (Chapters 24.1) Activity: Forensics and HWE
Week 12 - Mar 30 Quiz 7 Activity: Random genetic drift (p. 739) Patsalis et al. paper; Xu et al. paper HWE and selection (Chapter 14.2) Exam review Pedigree Go Fish
Week 13 - Apr 6 Exam 3: short answer Open review session Exam 3: problem solving Exam 3 followup
Week 14 - Apr 13 Quiz 8 Complementation (pp. 236-237) Spreadsheets and Selection Activity: Epistasis; Pleiotropy and Penetrance and Phenocopies, oh my! (Chapters 2.1-2.2)
Week 15 - Apr 20 Quiz 9 Catchup, open course review Lyons, Cox, and Dancis paper Activity: Doing the pathway shuffle (Genetics board game) Exam review
Week 16 - Apr 27 open course review Exam week


Grading

Quizzes (4 points each x 9)36 pts
Participation24 pts
Exam 128 pts
Exam 236 pts
Exam 336 pts
Final Exam40 pts
Total200 pts

If your final exam grade is higher than your average for the first three exams, your final exam grade will replace your lowest grade in Exams 1 through 3. So if you earn 90% on your final, and your exam average was 83%, and your lowest grade was a 70%, the 90% will replace the 70%, plus you get a 90% on the final.

A[190-200]
A-[180-190)
B+[173.4-180)
B[166.7-173.4)
B-[160-166.7)
C+[153.4-160)
C[146.7-153.4)
C-[140-146.7)
D[120-140)
F<120

Participation

Participation will be determined based upon a combination of factors, including but not limited to, attending sessions on time and for the full period (including recitations), participating in all iClicker questions for the day, and properly following any relevant RIT policies.


iClicker

We will be using iClicker to make our class time more engaging. This will help me understand what you know, give everyone a chance to participate, and increase how much you learn in class. This will also provide you with feedback on how well you are comprehending course concepts, and help you master challenging concepts.

You are required to participate with the iClicker student app on a smartphone, tablet or laptop in a timely fashion. It is also your responsibility to regularly check your iClicker records for any discrepancies.

You can use an existing iClicker account if you have one...please do not create a new account if you already have one. If you do not have an account yet, you can create a new iClicker account using the instructions here. There is a fee for using the iClicker service. Subscriptions can be purchased within the app.

Next, you can add our course per the instructions. The course will be under "Biology" and named "BIOL-321 Genetics 2026" for the Spring 2026 semester. It will be set up sometime in December 2025.


Optional homework assignments

The below homework questions are not required, but may be reflective of some questions on quizzes and exams. With the exception of dates without assigned problems, for every completed homework assignment submitted on paper in handwriting before the start of the following week (e.g. Homework for Week 1 due before class on Monday of Week 2), students will earn 1 bonus point toward their final grade. No late submissions, no matter how late, will be accepted for bonus points. Feedback will be given as quickly as possible.

All numbers below are Concepts in Action problems from the optional textbook from the end of the corresponding chapter. "2.1" corresponds to Chapter 2, first Concept in Action problem. All even numbered problems have answers in the back of the text. Problems from outside the textbook are also sometimes indicated.

Week AssignedWeek DueAssignment
1 2 start of recitation 2.1, 2.2, 2.5, 2.16, 2.20; Search OMIM for a disease of interest to you...in no more than one-half page, describe what is known about the genetics of this human trait.
2 3 3.2, 3.8, 6.4, 6.6, 6.8, 6.10
3 4 2.18, 3.10, 3.12, 5.4, 5.6, 5.8, 8.2, 8.6, 8.8, 8.14, 8.20, 12.2, 12.6, 12.8, 12.12, 12.16
4 5 9.2, 9.16, 9.18
5 6 9.6, 7.10, 7.11, 7.14, 7.18, 7.20
6 7 3.16, 3.18
7 8 Exam review packet
8 10 4.2, 4.6, 4.8, 4.10
9 N/A None
10 11 2.8, 2.9, 2.10, 2.21, 4.20 a & b, 5.12
11 12 14.2, 14.4, 14.6, 14.8, 14.10, 14.12
12 13 Exam review packet
13 14 HWE Worksheet in myCourses - Submit to myCourses Assignment box by Week 14 Friday
14 15 2.12, 2.14, 2.17, 4.13, 4.16, 4.20 (a and b), 15.2, 15.4, 15.10, 15.12, 15.20
15* 16* 2.3, 2.11, 2.15, 4.17, 9.13, 9.20, 12.9, 12.11, 14.9, 14.17, 2.13, 4.11 a-d, 4.14, 4.19, 9.15, 12.17, 14.11, 14.13, 14.15, 15.5
* Week 15 problems due before the final exam.

Quiz and Exam policy

No electronics except for a calculator. The calculator must not be a graphing or programmable calculator. No caps or hats.

Quizzes will take place during the first ten minutes of class time. Exams will take the full assigned session and you may leave when finished.

There will be one makeup for any exam or quiz, on a date and time to be determined by the instructor. Please email the instructor within 48 hours if you are unable to make an exam or quiz.


Recording policy

Unless written permission is granted by the faculty member, or a specific accommodation has been approved by the Disability Services Office, students are prohibited from recording lectures or presentations.


Plagiarism/cheating policy

For the first offense, anyone caught plagiarizing or otherwise cheating will receive a 0 (zero) on the assignment, and be referred to the Head of the School of Life Sciences. In the event of a second offense, the student will receive an "F" for the course. Duplicate submissions or excessive patchwriting will also receive a grade of 0 (zero) for the assignment. In the case of especially egregious offenses, the instructor reserves the right to assign a grade of "F" for the course, as per RIT policy.

If you have any questions about whether or not something constitutes plagiarism and/or cheating, please ask the instructor in advance.

Artificial Intelligence (AI) may not be used for assignments in this course except for the exploration of topics. Among other things, it may not be used for writing or drafting papers/reports. You may use it to get advice on how to do an analysis, for example. If you have any questions about acceptable use of AI in this course, please email the instructor immediately.


Links

Spreadsheets to practice with

Supporting information


Contents last updated 10/23/25